Polyphosphazenes—A Promising Candidate for Drug Delivery, Bioimaging, and Tissue Engineering: A Review
نویسندگان
چکیده
Synthetic polymer materials have been surged to the forefront of research in fields tissue engineering, drug delivery, and biomonitoring recent years. Biodegradable synthetic polymers are increasingly needed as transient substrates for regeneration medicine delivery. In contrast commonly used including polyesters, polylactones, polyanhydrides, poly(propylene fumarates), polyorthoesters, polyurethanes, biodegradable polyphosphazenes (PPZs) hold great potential purposes indicated above. PPZ's versatility process has enabled production a variety with various physico-chemical, biological properties produced, making them appropriate biomedical applications. Biocompatible PPZs often scaffolds skeleton, bones, other tissues. also received special attention vehicles high-value biopharmaceuticals such anticancer drugs. Additionally, by incorporating fluorophores into PPZ backbone produce photoluminescent PPZs, utility is further expanded they tracking target well fate based or delivery vehicles. This review provides summary evolution applications bioimaging 5
منابع مشابه
Hydroxyapatite from Fish for Bone Tissue Engineering: A Promising Approach
Natural or synthetic hydroxyapatite (HA) has been frequently used as implant materials for orthopaedic and dental applications, showing excellent bioactivity, adequate mechanical rigidity and structure, osteoconductivity and angiogenic properties, no toxicity, and absence of inflammatory or antigenic reactions. HA can be easily synthesized or extracted from natural sources, such as bovine bone....
متن کاملPhotoactivated drug delivery and bioimaging.
Among the various types of diseases, cancer remains one of the most leading causes of mortality that people are always suffering from and fighting with. So far, the effective cancer treatment demands accurate medical diagnosis, precise surgery, expensive medicine administration, which leads to a significant burden on patients, their families, and the whole national healthcare system around the ...
متن کاملPericyte-targeting drug delivery and tissue engineering
Pericytes are contractile mural cells that wrap around the endothelial cells of capillaries and venules. Depending on the triggers by cellular signals, pericytes have specific functionality in tumor microenvironments, properties of potent stem cells, and plasticity in cellular pathology. These features of pericytes can be activated for the promotion or reduction of angiogenesis. Frontier studie...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Macromolecular Materials and Engineering
سال: 2023
ISSN: ['1439-2054', '1438-7492']
DOI: https://doi.org/10.1002/mame.202200553